"...how can you justify spending perhaps $160 billion over the course of your tenure on marijuana prohibition? Isn't it the federal government, not us young people, that has irrationally prioritized marijuana policy?"

Obama Says Legalizing Marijuana Would Be 'Progress,' but Why the Rush? - Hit & Run : Reason.com: "Unlike other occasions when he was confronted by this subject, Obama does not laugh, but he does take the opportunity to lecture "young people" about their priorities. "I understand this is important to you," he says, "but, you know, you should be thinking about climate change, the economy, jobs, war and peace. Maybe, way at the bottom, you should be thinking about marijuana." 

As Conor Friedersdorf suggests at The Atlantic, there are sound reasons why people might disagree with the ordering Obama suggests, starting with the fact that marijuana prohibition is an obvious injustice with an obvious solution. Speaking as someone who is too old to qualify for Obama's age-based condescension, I think the chance that he and I will agree about marijuana legalization is much greater than the chance that we we will ever see eye to eye on the right approach to climate change, the government's proper role in promoting employment, or the justification for going to war...

The president is more comfortable criticizing "disproportionate prison sentences." He says "our criminal justice system" is "skewed towards cracking down on nonviolent drug offenders," which has "a terrible effect on many communities, particularly communities of color, rendering a lot of folks unemployable, because they [have] felony records." While "substance abuse...is a problem," Obama says, "locking someone up for 20 years is probably not the best strategy." He adds that he is "encouraged" that  "you're starting to see not just liberal Democrats but also some very conservative Republicans recognize this doesn't make sense, including the libertarian wing of the Republican Party." But here, too, Obama does not seem to think there is an urgent need for action, as reflected in his lackadaisical approach to clemency."

Vice News Editor Shane Smith Interviews President Barack Obama — The Atlantic: "Obama's skepticism of their priorities is ironic for the following reason: Implicit in the legalization movement is the notion that the president, the executive branch he presides over, and law enforcement all over America spend far too much time and far too many resources waging a doomed campaign against marijuana use. 

The young people to whom Obama addressed himself would be fully justified in reversing the criticism: "Given challenges like climate change, an uncertain economy, joblessness, and war, how can you justify spending perhaps $160 billion over the course of your tenure on marijuana prohibition? Isn't it the federal government, not us young people, that has irrationally prioritized marijuana policy? We're fighting for a more rational allotment of resources, where government funds are directed away from weed and toward challenges you listed as more pressing." 

Obama went on to speak as if he himself understands marijuana prohibition to be a policy with lots of awful consequences. "There is no doubt that our criminal justice system generally is so skewed toward cracking down on nonviolent drug offenders that it has not just had a terrible effect on many communities, particularly communities of color, rendering a lot of folks unemployable because they got felony records," he declared. "Disproportionate prison sentences. It costs a huge amount of money to states. And a lot of states are starting to figure that out." "