Carbohydrates control insulin; insulin regulates fat accumulation; chronically high insulin and insulin resistance lead to disease.

Outstanding article.

Zeroing In On Health – The Blog! Carbohydrates Kill People:

"I know, that appears to be quite a statement, but it’s true. Refined carbohydrates, starches and sugars are the dietary cause of coronary heart disease, and diabetes. They are the most likely causes of cancer, Alzheimer’s disease, and the other chronic diseases of civilization.

Carbohydrates affect insulin secretion by the pancreas and the more eaily digestible and refined the carbohydrates, the more chronic the effect on the hormonal regulation of homeostasis, the entire ensemble of the human body. This has an adverse affect on health, weight and well-being.

...What exactly regulates fat tissue? The answer is insulin. Carbohydrates increase insulin secretion, which increases hunger and decreases the amount of energy we expend in metabolism and physical activity. Theodore Van Itallie of Columbia University testified to McGovern’s Select Committee in 1973 that “There is an increased need for these vitamins when more carbohydrate in the diet is consumed.” Moreover, researchers have known since the 1930s that B vitamins are depleted from the body by the consumption of carbohydrates.

...In 1957, diabetologist George Campbell suggested an incubation period for diabetes. He found that amongst Zulu populations who worked in the physically demanding sugar cane industry that once sugar consumption reached 70 pounds per person, per year, the diseases of civilization would begin to appear. This same conclusion was drawn by missionary and colonial physicians who worked with isolated populations such as Schweitzer with African nations of the sub-Sahara, Hutton with the Eskimos of Laborador, or Hrdlicka with the Native American of the Great Plain. Once the people abandoned their native fat-rich diets and adopted the European dietary of refined and easily digestible carbohydrates, they could look forward to all the diseases of civilization, starting with dental caries all the way to dementia..."